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ANTACIDS AND LEVODOPA

Medical Diagnosis and Drugs, Medications
Antacids do not appear to interact significantly with immediate release levodopa, but they may reduce the bioavailability of modified release preparations of levodopa (e.g. A MadoparCR).
Concurrent use need not be avoided with standard preparations. With modified- release preparations it would seem advisable to avoid concurrent administration (2 to 3 hours is usually enough in other similar situations). The outcome should be monitored.
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