ANTACIDS AND PHENYTOIN
Some, but not all studies have shown that antacids (containing aluminium, calcium or magnesium) do not usually interact to a clinically relevant extent with phenytoin. However, in some instances antacids have reduced phenytoin serum levels and this may have been responsible for some loss of seizure control in a few patients.
Concurrent use need not be avoided but if there is any hint that an epileptic patient is being affected by this interaction, separating the dosages by 2 to 3 hours may minimise the effects.
Concurrent use need not be avoided but if there is any hint that an epileptic patient is being affected by this interaction, separating the dosages by 2 to 3 hours may minimise the effects.