.

ANTIDIABETICS AND FIBRATES - PIOGLITAZONE OR ROSIGLITAZONE

Medical Diagnosis and Drugs, Medications
Gemfibrozil causes large increases in the AUCs of pioglitazone and rosiglitazone.
The clinical relevance of this interaction has not been assessed. Until further experience is gained, caution is warranted. Consider an increased frequency of blood glucose monitoring when the combination is first started.
(4)