ANTIDIABETICS AND H2-RECEPTOR ANTAGONISTS - METFORMIN
Cimetidine appears to reduce the clearance of metformin, and may have contributed to a case of metformin-associated lactic acidosis.
It has been suggested that the dosage of metformin may need to be reduced if cimetidine is used, bearing in mind the possibility of lactic acidosis if levels become too high.
It has been suggested that the dosage of metformin may need to be reduced if cimetidine is used, bearing in mind the possibility of lactic acidosis if levels become too high.