ANTIDIABETICS AND HERBAL MEDICINES OR DIETARY SUPPLEMENTS - ST JOHN'S WORT (HYPERICUM PERFORATUM)
St John's wort decreased the AUC of rosiglitazone (modest decrease of about 25%).
The clinical relevance of the modest reduction in rosiglitazone levels has not been assessed, but it would seem unlikely to be important.
The clinical relevance of the modest reduction in rosiglitazone levels has not been assessed, but it would seem unlikely to be important.