ANTIPSYCHOTICS AND BETA BLOCKERS - SOTALOL
Additive QT-prolonging effects likely, see drugs that prolong the QT interval.
Concurrent use should generally be avoided.
Beta blockers, general
The concurrent use of chlorpromazine and propranolol can result in a marked rise in the plasma levels of both drugs. Propranolol also markedly increases plasma thioridazine levels. Additive hypotensive effects are also possible, see antihyperten- sives.
Monitor the outcome of concurrent use, adjusting the doses of both drugs as necessary.
Concurrent use should generally be avoided.
Beta blockers, general
The concurrent use of chlorpromazine and propranolol can result in a marked rise in the plasma levels of both drugs. Propranolol also markedly increases plasma thioridazine levels. Additive hypotensive effects are also possible, see antihyperten- sives.
Monitor the outcome of concurrent use, adjusting the doses of both drugs as necessary.