ANTIPSYCHOTICS AND DOPAMINE AGONISTS

Centrally-acting dopamine antagonists (such as the antipsychotics, including prochlorperazine used at an antiemetic dose) are expected to oppose the effects of the dopamine agonists.
Concurrent use should be avoided, or monitored closely to ensure that the dopamine agonist remains effective. Additive hypotensive effects possible, see antihypertensives