ASPIRIN AND CORTICOSTEROIDS
Serum salicylate levels are reduced by corticosteroids, and therefore salicylate levels may rise, possibly to toxic concentrations, if the corticosteroid is withdrawn without salicylate dosage adjustment. Concurrent use increases the risk of gastrointestinal bleeding and ulceration.
Patients taking high-dose salicylates should be monitored to ensure that the levels remain adequate when corticosteroids are added and do not become excessive if they are withdrawn.
Patients taking high-dose salicylates should be monitored to ensure that the levels remain adequate when corticosteroids are added and do not become excessive if they are withdrawn.