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AZOLES AND HERBAL MEDICINES OR DIETARY SUPPLEMENTS

Medical Diagnosis and Drugs, Medications
Two weeks of treatment with St John's wort (Hypericum perforatum) halved the levels of a single dose of voriconazole.
Patients requiring voriconazole should be asked about current or recent use of St John's wort, since they may be at risk of treatment failure. Monitor carefully. The manufacturers contraindicate concurrent use.
(2)