AZOLES AND SIROLIMUS - MICONAZOLE
Miconazole oral gel may be swallowed in large enough quantities to have a systemic interaction with sirolimus, which would be expected to result in raised sirolimus levels.
The manufacturers of miconazole oral gel recommend close monitoring and possible dose reduction of sirolimus if both drugs are given. An interaction with intravaginal miconazole would not normally be expected.
The manufacturers of miconazole oral gel recommend close monitoring and possible dose reduction of sirolimus if both drugs are given. An interaction with intravaginal miconazole would not normally be expected.