BENZODIAZEPINES AND DIGOXIN
Digoxin toxicity occurred in two elderly patients, and rises in serum digoxin levels have been seen in others, when they were given alprazolam. This interaction seems to occur particularly in patients over 65 years of age.
Monitor the effects of digoxin (e.g. bradycardia) in any patient if alprazolam is added and reduce the digoxin dosage as necessary.
Monitor the effects of digoxin (e.g. bradycardia) in any patient if alprazolam is added and reduce the digoxin dosage as necessary.