BETA BLOCKERS AND PROPAFENONE
Plasma metoprolol and propranolol levels can be markedly raised (2- to 5-fold) by propafenone. Toxicity may develop.
Information is limited. Anticipate the need to reduce the dosage of metoprolol and propranolol. Monitor closely. It is possible that other beta blockers that undergo liver metabolism will interact similarly but not those largely excreted unchanged in the urine (e.g. atenolol, nadolol). This needs confirmation.
Information is limited. Anticipate the need to reduce the dosage of metoprolol and propranolol. Monitor closely. It is possible that other beta blockers that undergo liver metabolism will interact similarly but not those largely excreted unchanged in the urine (e.g. atenolol, nadolol). This needs confirmation.