BUSPIRONE AND GRAPEFRUIT JUICE
Grapefruit juice can significantly increase plasma levels of buspirone (peak level increased by more than 4-fold, but a only minor increase in effects seen).
Consideration should be given to using a lower dose of buspirone, e.g. 2.5 mg twice daily, or avoidance of large quantities of grapefruit juice.
Consideration should be given to using a lower dose of buspirone, e.g. 2.5 mg twice daily, or avoidance of large quantities of grapefruit juice.