CALCIUM-CHANNEL BLOCKERS AND CORTICOSTEROIDS
Diltiazem increases the AUC of intravenous and oral methylprednisolone.
The clinical significance of this interaction is unclear. It has been suggested that patients should be monitored for methylprednisolone adverse effects (e.g. fluid retention, hypertension and hyperglycaemia), and this seems a prudent precau- tion.
The clinical significance of this interaction is unclear. It has been suggested that patients should be monitored for methylprednisolone adverse effects (e.g. fluid retention, hypertension and hyperglycaemia), and this seems a prudent precau- tion.