CALCIUM-CHANNEL BLOCKERS AND TACROLIMUS
Nifedipine causes a moderate rise in serum tacrolimus levels and also appears to be kidney protective. Diltiazem and felodipine also appear to elevate tacrolimus levels. Nicardipine, nilvadipine and verapamil are predicted to interact similarly.
Tacrolimus levels and/or effects (e.g. on renal function) should be monitored as a matter of routine, but consider increasing monitoring if one of these calcium- channel blockers is started or stopped.
Tacrolimus levels and/or effects (e.g. on renal function) should be monitored as a matter of routine, but consider increasing monitoring if one of these calcium- channel blockers is started or stopped.