CARBAMAZEPINE AND GRAPEFRUIT JUICE
Grapefruit juice increases carbamazepine levels by about 40%. A case of possible carbamazepine toxicity has been seen in a man taking carbamazepine after he started to eat grapefruit.
The manufacturers advise monitoring levels and adjusting the dose of carbama- zepine as necessary. If monitoring is not practical, or regular intake of grapefruit is not desired, it would seem prudent to avoid grapefruit or grapefruit juice.
The manufacturers advise monitoring levels and adjusting the dose of carbama- zepine as necessary. If monitoring is not practical, or regular intake of grapefruit is not desired, it would seem prudent to avoid grapefruit or grapefruit juice.