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CARBAMAZEPINE AND METHYLPHENIDATE

Medical Diagnosis and Drugs, Medications
Limited evidence suggests that carbamazepine may decrease methylphenidate levels.
It would seem wise to monitor the response to methylphenidate treatment carefully in patients taking carbamazepine. Note that the manufacturer says methylphenidate should be used with caution in patients with epilepsy, as it can, rarely, cause an increase in seizure frequency. If seizure frequency increases, methylphenidate should be discontinued.
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