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CARBAMAZEPINE AND TACROLIMUS

Medical Diagnosis and Drugs, Medications
Phenytoin decreased tacrolimus levels in one case, and has been used to reduce tacrolimus levels after an overdose. Other CYP3A4 inducers such as carbamazepine are predicted to interact similarly.
No interaction is established, but based on the known metabolism of these drugs it would be prudent to monitor tacrolimus levels in a patient given carbamazepine.
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