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CARBAMAZEPINE AND TETRACYCLINES

Medical Diagnosis and Drugs, Medications
The serum levels of doxycycline are reduced and may fall below the accepted therapeutic minimum in patients taking carbamazepine long-term.
It has been suggested that the doxycycline dosage could be doubled to counteract this interaction. Tetracycline, oxytetracycline and chlortetracycline appear not to interact and may therefore be suitable alternatives.
(3)