CASPOFUNGIN AND TACROLIMUS
Caspofungin decreases trough tacrolimus levels by 26%. Tacrolimus does not affect the pharmacokinetics of caspofungin.
Tacrolimus levels and/or effects (e.g. on renal function) should be monitored as a matter of routine, but it is advisable to increase monitoring if caspofungin is started or stopped, and adjust the dose of tacrolimus if required.
Tacrolimus levels and/or effects (e.g. on renal function) should be monitored as a matter of routine, but it is advisable to increase monitoring if caspofungin is started or stopped, and adjust the dose of tacrolimus if required.