CHLOROQUINE AND H2-RECEPTOR ANTAGONISTS
Cimetidine reduces the metabolism and halves the clearance of chloroquine.
The clinical importance of this interaction is uncertain, but it would seem prudent to be alert for any signs of chloroquine toxicity during concurrent use. Hydroxychloroquine is expected to be similarly affected. Ranitidine may be a suitable alternative as it does not appear to interact.
The clinical importance of this interaction is uncertain, but it would seem prudent to be alert for any signs of chloroquine toxicity during concurrent use. Hydroxychloroquine is expected to be similarly affected. Ranitidine may be a suitable alternative as it does not appear to interact.