CICLOSPORIN (CYCLOSPORINE) AND H2-RECEPTOR ANTAGONISTS
Although some reports suggest that cimetidine (and possibly famotidine) can rarely increase ciclosporin levels, the majority of the information suggests no interaction occurs. Note that raised creatinine levels have been seen following the combination, but this does not appear to be related to renal toxicity or reduced renal function.
There is little to suggest that concurrent use should be avoided, but good initial monitoring is advisable.
There is little to suggest that concurrent use should be avoided, but good initial monitoring is advisable.