
CINACALCET AND RIFAMPICIN (RIFAMPIN)
Rifampicin is predicted to decrease cinacalcet levels by inducing its metabolism by CYP3A4. This seems a reasonable prediction as potent CYP3A4 inhibitors raise cinacalcet levels.
It may be prudent to monitor parathyroid hormone and serum calcium more frequently if rifampicin is started or stopped.
It may be prudent to monitor parathyroid hormone and serum calcium more frequently if rifampicin is started or stopped.