
CLONIDINE AND LEVODOPA
Limited evidence suggests that the control of Parkinson's disease with levodopa may be impaired by clonidine.
Be alert for a reduction in the control of the Parkinson's disease during concurrent use. The effects of this interaction appear to be reduced if antimuscarinic drugs are also being used. Be aware that, as with all antihypertensives, additive hypotensive effects may occur with levodopa, see antihypertensives.
Be alert for a reduction in the control of the Parkinson's disease during concurrent use. The effects of this interaction appear to be reduced if antimuscarinic drugs are also being used. Be aware that, as with all antihypertensives, additive hypotensive effects may occur with levodopa, see antihypertensives.