CO-TRIMOXAZOLE AND PHENYTOIN
Phenytoin serum levels can be raised by co-trimoxazole. Phenytoin toxicity may
develop in some cases.
The risk of toxicity is small and is most likely in those with serum phenytoin levels at the top end of the range. Monitor phenytoin levels and adjust the dose accordingly. Indicators of phenytoin toxicity include blurred vision, nystagmus, ataxia or drowsiness.
develop in some cases.
The risk of toxicity is small and is most likely in those with serum phenytoin levels at the top end of the range. Monitor phenytoin levels and adjust the dose accordingly. Indicators of phenytoin toxicity include blurred vision, nystagmus, ataxia or drowsiness.