COLESTYRAMINE AND RELATED DRUGS AND LEFLUNOMIDE
Studies have shown that colestyramine reduces the serum levels of the active
metabolite of leflunomide by up to 65%.
Patients taking leflunomide should not be given colestyramine unless it is needed to washout' the leflunomide, such as in overdosage or when switching to another DMARD.
metabolite of leflunomide by up to 65%.
Patients taking leflunomide should not be given colestyramine unless it is needed to washout' the leflunomide, such as in overdosage or when switching to another DMARD.