CONTRACEPTIVES AND GRISEOFULVIN
The effects of the oral contraceptives may possibly be disturbed (either inter-menstrual
bleeding or amenorrhoea) if griseofulvin is taken concurrently. There are reports of 4
women taking oral contraceptives who became pregnant while taking griseofulvin.
Similarly, progestogen-only emergency hormonal contraceptives are considered to be
less effective in those taking griseofulvin. The situation with progestogen-only oral
contraceptives is not clear, but it has been suggested that they are not the
contraceptive of choice in those taking griseofulvin because of increased menstrual
irregularities.
As griseofulvin is potentially teratogenic it has been recommended that a barrier method is used during and for 1 month after taking griseofulvin. For general advice on the use of enzyme inducers, such as griseofulvin, and contraceptives, see contraceptives.
bleeding or amenorrhoea) if griseofulvin is taken concurrently. There are reports of 4
women taking oral contraceptives who became pregnant while taking griseofulvin.
Similarly, progestogen-only emergency hormonal contraceptives are considered to be
less effective in those taking griseofulvin. The situation with progestogen-only oral
contraceptives is not clear, but it has been suggested that they are not the
contraceptive of choice in those taking griseofulvin because of increased menstrual
irregularities.
As griseofulvin is potentially teratogenic it has been recommended that a barrier method is used during and for 1 month after taking griseofulvin. For general advice on the use of enzyme inducers, such as griseofulvin, and contraceptives, see contraceptives.