CONTRACEPTIVES AND QUINOLONES
Ciprofloxacin, moxifloxacin and ofloxacin have been shown not to affect the pharmacokinetics of the combined oral contraceptives in controlled studies. Contra- ceptive failure does not appear to have been reported, and ovarian suppression is not affected.
It is possible that the anecdotal cases of contraceptive failure with antibacterials are indistinguishable from the normal accepted failure rate and no special precautions are required. However, some specialists recommend that additional contraceptives, such as condoms, should be used for short courses of antibacterials. For guidance on the use of antibacterials with contraceptives, see contracep- tives.
It is possible that the anecdotal cases of contraceptive failure with antibacterials are indistinguishable from the normal accepted failure rate and no special precautions are required. However, some specialists recommend that additional contraceptives, such as condoms, should be used for short courses of antibacterials. For guidance on the use of antibacterials with contraceptives, see contracep- tives.