CONTRACEPTIVES AND TETRACYCLINES

Contraceptive failure has been attributed to a tetracycline in about 40 reported cases, 7 of which specified long-term antibacterial use. The interaction (if such it is) appears to be very rare. Controlled studies have not found that tetracyclines affect contracep- tive steroid levels.
For guidance on the use of antibacterials with contraceptives, see contraceptives.