CONTRACEPTIVES AND TOPIRAMATE
The serum levels of ethinylestradiol are moderately reduced by topiramate, which increases the risk of breakthrough bleeding and possible contraceptive failure in women taking combined hormonal contraceptives. Similarly, emergency hormonal contraceptives are considered to be less effective in those taking topiramate.
Topiramate is a weak enzyme inducer. However, the potential for contraceptive failure still exists. The manufacturers advise that patients should be told to report any changes in their bleeding patterns. For advice on the use of enzyme inducers, such as topiramate, and contraceptives, see contraceptives.
Topiramate is a weak enzyme inducer. However, the potential for contraceptive failure still exists. The manufacturers advise that patients should be told to report any changes in their bleeding patterns. For advice on the use of enzyme inducers, such as topiramate, and contraceptives, see contraceptives.