
CONTRACEPTIVES AND WARFARIN AND OTHER ORAL ANTICOAGULANTS
The anticoagulant effects of dicoumarol and phenprocoumon can be decreased, and those of acenocoumarol increased, by hormonal contraceptives. An isolated report describes a marked INR increase in a woman taking warfarin when she was given levonorgestrel emergency contraception. A report describes a woman who needed more acenocoumarol when her HRT treatment with oral conjugated oestrogens was changed to transdermal estradiol.
Direct information is limited. Combined hormonal contraceptives are usually contraindicated in patients with thromboembolic disorders. However, if they are used be aware that the anticoagulant response may be affected.
Direct information is limited. Combined hormonal contraceptives are usually contraindicated in patients with thromboembolic disorders. However, if they are used be aware that the anticoagulant response may be affected.