DANAZOL AND SIROLIMUS
The manufacturers predict that the serum levels of sirolimus will be increased by danazol. Note that similar predictions have proven to be true with ciclosporin (cyclosporine) and tacrolimus.
Sirolimus levels and/or effects (e.g. on renal function) should be monitored as a matter of routine, but it may be prudent to increase monitoring if danazol is started or stopped.
Sirolimus levels and/or effects (e.g. on renal function) should be monitored as a matter of routine, but it may be prudent to increase monitoring if danazol is started or stopped.