DAPSONE AND RIFABUTIN
Rifabutin increases the clearance of dapsone, but may also increase its toxicity (methaemoglobinaemia).
Concurrent use should be well monitored to confirm that treatment is effective. It may be necessary to raise the dosage of dapsone. Also be alert for any evidence of methaemoglobinaemia.
Concurrent use should be well monitored to confirm that treatment is effective. It may be necessary to raise the dosage of dapsone. Also be alert for any evidence of methaemoglobinaemia.