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DIGOXIN AND LITHIUM

Medical Diagnosis and Drugs, Medications
No pharmacokinetic interaction seems to occur between digoxin and lithium. However, the addition of digoxin to lithium possibly has a short-term detrimental effect on the control of mania. An isolated report describes severe bradycardia in one patient given both drugs.
The probability of a clinically significant interaction occurring seems low, but bear these cases in mind if both drugs are given.
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