DIGOXIN AND PROPAFENONE
Propafenone can increase serum digoxin levels by 30 to 90% or more (particularly in children).
Most patients appear to be affected and dosage reductions in the range of 15 to 70% were found necessary in one study. The extent of the rise may possibly depend on the propafenone level rather than on the propafenone dose. Monitor digoxin levels and adjust the dose accordingly.
Most patients appear to be affected and dosage reductions in the range of 15 to 70% were found necessary in one study. The extent of the rise may possibly depend on the propafenone level rather than on the propafenone dose. Monitor digoxin levels and adjust the dose accordingly.