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DIGOXIN AND QUINIDINE

Medical Diagnosis and Drugs, Medications
Quinidine, on average, doubles the serum levels of digoxin in most patients within 5 days of concurrent use.
Halve the digoxin dose, monitor digoxin levels and further adjust the dose as necessary. Patients with renal impairment may require larger dose reductions. Remember to increase the digoxin dose if quinidine is stopped.
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