DIGOXIN AND TOPIRAMATE
Topiramate slightly reduces the maximum levels and AUC of digoxin by less than 20%.
The manufacturer suggests good monitoring of digoxin if topiramate is added or withdrawn, but changes of this magnitude seem unlikely to be clinically relevant in most patients.
The manufacturer suggests good monitoring of digoxin if topiramate is added or withdrawn, but changes of this magnitude seem unlikely to be clinically relevant in most patients.