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DIURETICS AND LITHIUM - SPIRONOLACTONE

Medical Diagnosis and Drugs, Medications
One study found that spironolactone caused the lithium levels to rise from 0.63 to 0.9 mmol/L. However, another study found no interaction.
Evidence for this interaction is sparse, no additional monitoring is necessary, but patients on lithium should be aware of the symptoms of lithium toxicity and told to report them immediately should they occur.
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