
DIURETICS AND PROTEASE INHIBITORS
Saquinavir increases the AUC of eplerenone 2.1-fold. The manufacturer predicts that nelfinavir and ritonavir will interact to a greater extent.
The manufacturer recommends a maximum eplerenone dose of 25 mg daily in
those taking saquinavir. Because they predict a greater effect with nelfinavir and ritonavir they contraindicate the concurrent use of these protease inhibitors.
The manufacturer recommends a maximum eplerenone dose of 25 mg daily in
those taking saquinavir. Because they predict a greater effect with nelfinavir and ritonavir they contraindicate the concurrent use of these protease inhibitors.