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DOPAMINE AGONISTS AND SSRIS

Medical Diagnosis and Drugs, Medications
Ciprofloxacin increases the AUC of ropinirole by 84%. The manufacturers therefore predict that other CYP1A2 inhibitors (they name fluvoxamine) will interact similarly.
The clinical relevance of this pharmacokinetic interaction has not been assessed. The manufacturers suggest that the ropinirole dose may need to be adjusted in patients taking fluvoxamine.
(1)