DOXAPRAM AND THEOPHYLLINE
No pharmacokinetic interaction appears to occur between theophylline and doxapram in neonates. However, the manufacturers of doxapram say that clinical data suggests there may be an interaction (not confined to neonates), which is manifested by agitation and increased skeletal muscle activity.
Although this reaction seems rare, it would be prudent to monitor concurrent use for any adverse outcome.
Although this reaction seems rare, it would be prudent to monitor concurrent use for any adverse outcome.