EZETIMIBE AND STATINS
No pharmacokinetic interaction appears to occur between ezetimibe and the statins, but the incidence of rhabdomyolysis may be increased on concurrent use. Note that the use of ezetimibe and a statin results in additive lipid-lowering effects, and combination preparations are available.
Patients taking statins should be counselled regarding myopathy (e.g. report any unexplained muscle pain, tenderness or weakness). This should be reinforced if they are also given ezetimibe.
Patients taking statins should be counselled regarding myopathy (e.g. report any unexplained muscle pain, tenderness or weakness). This should be reinforced if they are also given ezetimibe.