FELBAMATE AND VALPROATE
Felbamate can raise sodium valproate serum levels (by up to about 50% with a 2.4 g dose of felbamate), which may cause toxicity. Valproate may slightly decrease the clearance of felbamate.
Monitor the outcome of concurrent use. Monitor valproate levels if toxicity is suspected. Be aware that the felbamate dose may need to be decreased.
Monitor the outcome of concurrent use. Monitor valproate levels if toxicity is suspected. Be aware that the felbamate dose may need to be decreased.