FELBAMATE (FELBATOL)
Felbamate (Felbatol); Anticonvulsant; Susp: 600 mg/5 mL
Tab: 400, 600 mg ; 2-14 yrs: Initial: 15 mg/kg/day PO tid-qid; titrate by 15 mg/kg/day at weekly intervals to max of 45 mg/kg/day or 3600 mg/day
(whichever is less) tid-qid
>14 yrs: Initial: 1200 mg/day PO tid-qid; titrate by 600 mg/day increments at 2-wk intervals prn until max of 3600 mg/day
Increases concentrations of phenytoin and valproic acid. Associated with aplastic anemia and acute liver failure; therefore, not a first-line
anticonvulsant. Written informed consent necessary. Monitor CBC, liver function, and bilirubin.
Tab: 400, 600 mg ; 2-14 yrs: Initial: 15 mg/kg/day PO tid-qid; titrate by 15 mg/kg/day at weekly intervals to max of 45 mg/kg/day or 3600 mg/day
(whichever is less) tid-qid
>14 yrs: Initial: 1200 mg/day PO tid-qid; titrate by 600 mg/day increments at 2-wk intervals prn until max of 3600 mg/day
Increases concentrations of phenytoin and valproic acid. Associated with aplastic anemia and acute liver failure; therefore, not a first-line
anticonvulsant. Written informed consent necessary. Monitor CBC, liver function, and bilirubin.