GRAPEFRUIT JUICE AND TACROLIMUS
Grapefruit juice can markedly increase the serum levels of tacrolimus (by up to 400% in one study).
Tacrolimus levels and effects (e.g. on renal function) should be monitored as a matter of routine, but it is advisable to increase monitoring if grapefruit juice is started or stopped, or avoid the combination.
Tacrolimus levels and effects (e.g. on renal function) should be monitored as a matter of routine, but it is advisable to increase monitoring if grapefruit juice is started or stopped, or avoid the combination.