H2-RECEPTOR ANTAGONISTS AND PROCAINAMIDE
Cimetidine can increase procainamide levels by more than 50%, which may lead to procainamide toxicity.
Patients, particularly the elderly, should be closely monitored for signs of procainamide toxicity, and a dose reduction should be considered. Ranitidine
and famotidine appear to interact only minimally or not at all.
Patients, particularly the elderly, should be closely monitored for signs of procainamide toxicity, and a dose reduction should be considered. Ranitidine
and famotidine appear to interact only minimally or not at all.