H2-RECEPTOR ANTAGONISTS AND QUININE
The clearance of quinine is reduced by cimetidine, resulting in a 42% increase in the AUC of quinine.
The clinical importance of this is uncertain, but be particularly alert for any evidence of quinine adverse effects during concurrent use. Note that ranitidine appears not to interact.
The clinical importance of this is uncertain, but be particularly alert for any evidence of quinine adverse effects during concurrent use. Note that ranitidine appears not to interact.