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H2-RECEPTOR ANTAGONISTS AND SIROLIMUS

Medical Diagnosis and Drugs, Medications
The manufacturers of sirolimus predict that its serum levels will be increased by
cimetidine.
Sirolimus levels and/or effects (e.g. on renal function) should be monitored as a
matter of routine, but it may be prudent to increase monitoring if cimetidine is
started or stopped.
(1)