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HERBAL MEDICINES OR DIETARY SUPPLEMENTS AND PROTEASE INHIBITORS - GARLIC

Medical Diagnosis and Drugs, Medications
A garlic supplement reduced the plasma levels of saquinavir by 50%.
All garlic supplements should probably be avoided if saquinavir is ever given as the sole protease inhibitor (not recommended). The clinical relevance of this interaction with boosted saquinavir is unclear, but note that no significant interaction appears to occur with ritonavir.
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