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HERBAL MEDICINES OR DIETARY SUPPLEMENTS AND PROTON PUMP INHIBITORS

Medical Diagnosis and Drugs, Medications
Both Gingko biloba and St John’s wort (Hypericum perforatum) induce the metabolism of omeprazole, and this might result in reduced efficacy. Other proton pump inhibitors are likely to be similarly affected.
There is insufficient evidence to suggest that these herbs should be avoided in
patients taking proton pump inhibitors. However, the potential reduction in their
efficacy should be borne in mind, particular where the consequences may be serious, such as in patients with healing ulcers. Note that rabeprazole seems less likely to be affected.
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